Assay Detail
Binding
CHEMBL928875
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Inhibition of Met
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Intermediate |
Publication
Identification of 2-amino-5-(thioaryl)thiazoles as inhibitors of nerve growth factor receptor TrkA.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 6.57 | 6.77 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL251796 | — | — | 1 | 6.77 |
| CHEMBL254895 | — | — | 1 | 6.37 |
| CHEMBL254050 | — | — | 1 | - |
| CHEMBL251795 | — | — | 1 | - |
| CHEMBL254269 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL251796 | — | IC50 | = | 170.0 | nM | 6.77 |
| CHEMBL254895 | — | IC50 | = | 430.0 | nM | 6.37 |
| CHEMBL254050 | — | IC50 | > | 1000.0 | nM | - |
| CHEMBL251795 | — | IC50 | > | 1000.0 | nM | - |
| CHEMBL254269 | — | IC50 | > | 1000.0 | nM | - |