Assay Detail
Functional
CHEMBL929574
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Cytotoxicity against human MDA-MB cells under deem light after 96 hrs by MTT assay
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | MDA-MB |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Preparation and in vitro biological evaluation of tetrapyrrole ethanolamide derivatives as potential anticancer agents.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 4.63 | 5.05 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL53463 | DOXORUBICIN | 4.0 | 1 | 5.05 |
| CHEMBL269813 | HEMATOPORPHYRIN PROPYLETHER ETHANOLAMIDE | — | 1 | 4.92 |
| CHEMBL257049 | PHEOPHORBIDE A ETHANOLAMIDE | — | 1 | 4.46 |
| CHEMBL270363 | POLYHEMATOPORPHYRIN | — | 1 | 4.07 |
| CHEMBL504821 | METHYL PHEOPHORBIDE A | — | 1 | - |
| CHEMBL317840 | HAEMAPORPHYRIN | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL53463 | DOXORUBICIN | IC50 | = | 9000.0 | nM | 5.05 |
| CHEMBL269813 | HEMATOPORPHYRIN PROPYLETHER ETHANOLAMIDE | IC50 | = | 12000.0 | nM | 4.92 |
| CHEMBL257049 | PHEOPHORBIDE A ETHANOLAMIDE | IC50 | = | 35000.0 | nM | 4.46 |
| CHEMBL270363 | POLYHEMATOPORPHYRIN | IC50 | = | 85000.0 | nM | 4.07 |
| CHEMBL504821 | METHYL PHEOPHORBIDE A | IC50 | > | 100000.0 | nM | - |
| CHEMBL317840 | HAEMAPORPHYRIN | IC50 | > | 100000.0 | nM | - |