Assay Detail
Functional
CHEMBL929609
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Antiproliferative activity against human HL60 cells after 72 hrs by WST1 based assay
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | HL-60 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
New cytotoxic saturated and unsaturated cyclohexanones from Anthemis maritima.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 5.41 | 6.05 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4298697 | — | — | 1 | 6.05 |
| CHEMBL252202 | ANTHEMINONE C | — | 1 | 5.50 |
| CHEMBL400418 | ANTHEMINONE A | — | 1 | 5.12 |
| CHEMBL252005 | ANTHEMINONE B | — | 1 | 4.96 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4298697 | — | IC50 | = | 900.0 | nM | 6.05 |
| CHEMBL252202 | ANTHEMINONE C | IC50 | = | 3200.0 | nM | 5.50 |
| CHEMBL400418 | ANTHEMINONE A | IC50 | = | 7600.0 | nM | 5.12 |
| CHEMBL252005 | ANTHEMINONE B | IC50 | = | 11000.0 | nM | 4.96 |