Assay Detail
Functional
CHEMBL929647
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Cytotoxicity against human 2780.9S cells under deem light after 96 hrs by MTT assay
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Preparation and in vitro biological evaluation of tetrapyrrole ethanolamide derivatives as potential anticancer agents.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 4.57 | 4.82 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL53463 | DOXORUBICIN | 4.0 | 1 | 4.82 |
| CHEMBL269813 | HEMATOPORPHYRIN PROPYLETHER ETHANOLAMIDE | — | 1 | 4.80 |
| CHEMBL257049 | PHEOPHORBIDE A ETHANOLAMIDE | — | 1 | 4.46 |
| CHEMBL270363 | POLYHEMATOPORPHYRIN | — | 1 | 4.19 |
| CHEMBL504821 | METHYL PHEOPHORBIDE A | — | 1 | - |
| CHEMBL317840 | HAEMAPORPHYRIN | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL53463 | DOXORUBICIN | IC50 | = | 15000.0 | nM | 4.82 |
| CHEMBL269813 | HEMATOPORPHYRIN PROPYLETHER ETHANOLAMIDE | IC50 | = | 16000.0 | nM | 4.80 |
| CHEMBL257049 | PHEOPHORBIDE A ETHANOLAMIDE | IC50 | = | 35000.0 | nM | 4.46 |
| CHEMBL270363 | POLYHEMATOPORPHYRIN | IC50 | = | 65000.0 | nM | 4.19 |
| CHEMBL504821 | METHYL PHEOPHORBIDE A | IC50 | > | 100000.0 | nM | - |
| CHEMBL317840 | HAEMAPORPHYRIN | IC50 | > | 100000.0 | nM | - |