Assay Detail
Binding
CHEMBL931626
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Inhibition of wild type HDAC4 expressed in Escherichia coli
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Probing the elusive catalytic activity of vertebrate class IIa histone deacetylases.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 6.31 | 7.48 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL115011 | — | — | 1 | 7.48 |
| CHEMBL356066 | DACINOSTAT | 2.0 | 1 | 6.38 |
| CHEMBL430060 | APICIDIN | — | 1 | 5.06 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL115011 | — | IC50 | = | 33.0 | nM | 7.48 |
| CHEMBL356066 | DACINOSTAT | IC50 | = | 420.0 | nM | 6.38 |
| CHEMBL430060 | APICIDIN | IC50 | = | 8700.0 | nM | 5.06 |