Assay Detail
Binding
CHEMBL931724
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of Escherichia coli MTAN
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Escherichia coli |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Target
5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase (CHEMBL1250346) ↗| Type | SINGLE PROTEIN |
| Organism | Escherichia coli O157:H7 |
Publication
Azetidine based transition state analogue inhibitors of N-ribosyl hydrolases and phosphorylases.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 9.22 | 9.35 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL405371 | — | — | 1 | 9.35 |
| CHEMBL407216 | — | — | 1 | 9.08 |
| CHEMBL405346 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL405371 | — | Ki | = | 0.45 | nM | 9.35 |
| CHEMBL407216 | — | Ki | = | 0.84 | nM | 9.08 |
| CHEMBL405346 | — | Ki | = | 0.002 | nM | - |