Assay Detail
Functional
CHEMBL932500
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Induction of cell death in human HT1080 cells in presence of PD-98059 by trypan blue exclusion method
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | HT-1080 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
RAS-RAF-MEK-dependent oxidative cell death involving voltage-dependent anion channels.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 6.00 | 6.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL401989 | ERASTIN | — | 1 | 6.00 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL401989 | ERASTIN | IC50 | = | 1000.0 | nM | 6.00 |