Assay Detail
Binding
CHEMBL932683
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Displacement of [3H]SCH-23390 from rat HA-tagged D1 dopamine receptor expressed in CHO cells
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Rattus norvegicus |
| Cell Type | CHO |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Novel coumarin glycoside and phenethyl vanillate from Notopterygium forbesii and their binding affinities for opioid and dopamine receptors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 6.29 | 6.72 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL69018 | FALCARINDIOL | — | 1 | 6.72 |
| CHEMBL258939 | NOTOPTEROL | — | 1 | 5.85 |
| CHEMBL408980 | ANISOCOUMARIN H | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL69018 | FALCARINDIOL | Ki | = | 192.0 | nM | 6.72 |
| CHEMBL258939 | NOTOPTEROL | Ki | = | 1422.0 | nM | 5.85 |
| CHEMBL408980 | ANISOCOUMARIN H | Ki | > | 10000.0 | nM | - |