Assay Detail
Functional
CHEMBL933013
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Inhibition of NO production in LPS-activated mouse BV2 cells by ELISA
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Mus musculus |
| Cell Type | BV-2 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Inhibition of lipopolysaccharide-induced inducible nitric oxide synthase and cyclooxygenase-2 expression by xanthanolides isolated from Xanthium strumarium.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 5.64 | 6.33 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL404466 | — | — | 1 | 6.33 |
| CHEMBL257513 | — | — | 1 | 4.95 |
| CHEMBL256171 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL404466 | — | IC50 | = | 470.0 | nM | 6.33 |
| CHEMBL257513 | — | IC50 | = | 11200.0 | nM | 4.95 |
| CHEMBL256171 | — | IC50 | = | 136500.0 | nM | - |