Assay Detail
Functional
CHEMBL933034
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Agonist activity at human MC4 receptor expressed in HEK293 cells
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | HEK293 |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Synthesis and biological activity of novel peptide mimetics as melanocortin receptor agonists.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 7 | 8.40 | 9.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL339053 | — | — | 1 | 9.00 |
| CHEMBL272099 | — | — | 1 | 7.80 |
| CHEMBL429742 | — | — | 1 | - |
| CHEMBL256630 | — | — | 1 | - |
| CHEMBL258295 | — | — | 1 | - |
| CHEMBL257040 | — | — | 1 | - |
| CHEMBL403722 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL339053 | — | EC50 | = | 1.0 | nM | 9.00 |
| CHEMBL272099 | — | EC50 | = | 16.0 | nM | 7.80 |
| CHEMBL429742 | — | EC50 | > | 100000.0 | nM | - |
| CHEMBL256630 | — | EC50 | > | 50000.0 | nM | - |
| CHEMBL258295 | — | EC50 | > | 100000.0 | nM | - |
| CHEMBL257040 | — | EC50 | > | 50000.0 | nM | - |
| CHEMBL403722 | — | EC50 | > | 25000.0 | nM | - |