Assay Detail
Functional
CHEMBL933209
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Activity at mouse CB1 receptor in mouse N18TG2 cells assessed as forskolin-induced cAMP formation
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Mus musculus |
| Cell Type | N18TG2 |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Synthesis, cannabinoid receptor affinity, and molecular modeling studies of substituted 1-aryl-5-(1H-pyrrol-1-yl)-1H-pyrazole-3-carboxamides.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 3 | 8.30 | 9.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL272203 | — | — | 1 | 9.00 |
| CHEMBL410727 | — | — | 1 | 7.60 |
| CHEMBL409150 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL272203 | — | EC50 | = | 1.0 | nM | 9.00 |
| CHEMBL410727 | — | EC50 | = | 25.0 | nM | 7.60 |
| CHEMBL409150 | — | EC50 | > | 60.0 | nM | - |