Assay Detail
Binding
CHEMBL933247
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of human cathepsin G
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Discovery of a potent, selective, and orally active proteasome inhibitor for the treatment of cancer.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 5.98 | 6.28 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL325041 | BORTEZOMIB | 3.0 | 1 | 6.28 |
| CHEMBL270515 | DELANZOMIB | 2.0 | 1 | 5.68 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL325041 | BORTEZOMIB | IC50 | = | 520.0 | nM | 6.28 |
| CHEMBL270515 | DELANZOMIB | IC50 | = | 2110.0 | nM | 5.68 |