Assay Detail
Binding
CHEMBL933386
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Binding affinity to truncated iNOS construct (1-490) by spectral assay
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
N(G)-aminoguanidines from primary amines and the preparation of nitric oxide synthase inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 5 | 5.00 | 5.89 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL405231 | — | — | 1 | 5.89 |
| CHEMBL1485 | ARGININE | 3.0 | 1 | 5.16 |
| CHEMBL408756 | — | — | 1 | 5.00 |
| CHEMBL272814 | — | — | 1 | 4.54 |
| CHEMBL272851 | — | — | 1 | 4.39 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL405231 | — | Kd | = | 1300.0 | nM | 5.89 |
| CHEMBL1485 | ARGININE | Kd | = | 7000.0 | nM | 5.16 |
| CHEMBL408756 | — | Kd | = | 10000.0 | nM | 5.00 |
| CHEMBL272814 | — | Kd | = | 29000.0 | nM | 4.54 |
| CHEMBL272851 | — | Kd | = | 40400.0 | nM | 4.39 |