Assay Detail

CHEMBL934097

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Functional

Anticancer activity against multidrug-resistant human KBV1 cells

ChEMBL ↗

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Target

NON-PROTEIN TARGET (CHEMBL3879801) ↗

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Primary target NON-PROTEIN TARGET

CHEMBL3879801

Anchored from Assay target.

Protein identity NON-PROTEIN TARGET

Disease frame Disease evidence pending

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Review focus Open DB context pending

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Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Functional
Organism	Homo sapiens
Cell Type	KB-V1
Confidence	1 — Organism
Curated By	Autocuration

Target

NON-PROTEIN TARGET (CHEMBL3879801) ↗

Type	NON-MOLECULAR

Publication

Cytotoxic simplified tubulysin analogues.

Raghavan B, Balasubramanian R, Steele JC, Sackett DL, Fecik RA.
J Med Chem (2008) 51 : 1530 -1533
PubMed 18314944 · DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
IC50	1	9.51	9.51

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL455213	TUBULYSIN D	—	1	9.51

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL455213	TUBULYSIN D	IC50	=	0.31	nM	9.51