Assay Detail
Binding
CHEMBL934553
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding affinity to mu opioid receptor in Sprague-Dawley rat brain membrane
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Rattus norvegicus |
| Tissue | Brain |
| Subcellular | Membrane |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Role of benzimidazole (Bid) in the delta-opioid agonist pseudopeptide H-Dmt-Tic-NH-CH(2)-Bid (UFP-502).
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 7 | 9.02 | 9.80 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL260127 | — | — | 1 | 9.80 |
| CHEMBL109390 | — | — | 1 | 9.30 |
| CHEMBL408975 | — | — | 1 | 9.15 |
| CHEMBL258704 | — | — | 1 | 8.97 |
| CHEMBL407957 | — | — | 1 | 8.93 |
| CHEMBL258458 | — | — | 1 | 8.85 |
| CHEMBL259917 | — | — | 1 | 8.17 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL260127 | — | Ki | = | 0.16 | nM | 9.80 |
| CHEMBL109390 | — | Ki | = | 0.5 | nM | 9.30 |
| CHEMBL408975 | — | Ki | = | 0.7 | nM | 9.15 |
| CHEMBL258704 | — | Ki | = | 1.06 | nM | 8.97 |
| CHEMBL407957 | — | Ki | = | 1.18 | nM | 8.93 |
| CHEMBL258458 | — | Ki | = | 1.42 | nM | 8.85 |
| CHEMBL259917 | — | Ki | = | 6.74 | nM | 8.17 |