Assay Detail
Functional
CHEMBL934556
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Agonist activity at delta opioid receptor assessed as inhibition of electrically-stimulated mouse vas deferens contraction
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Mus musculus |
| Tissue | Vas deferens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Role of benzimidazole (Bid) in the delta-opioid agonist pseudopeptide H-Dmt-Tic-NH-CH(2)-Bid (UFP-502).
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 8.12 | 9.03 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL109390 | — | — | 1 | 9.03 |
| CHEMBL407957 | — | — | 1 | 8.44 |
| CHEMBL260127 | — | — | 1 | 6.89 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL109390 | — | IC50 | = | 0.94 | nM | 9.03 |
| CHEMBL407957 | — | IC50 | = | 3.63 | nM | 8.44 |
| CHEMBL260127 | — | IC50 | = | 129.0 | nM | 6.89 |