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Assay Detail

CHEMBL935059

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antiviral activity against C clade R5 tropic HIV1 97ZA009 in HeLa H1-JC.37 cells by focal infectivity assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Human immunodeficiency virus 1
Cell Type HeLa
Confidence 1 — Organism
Curated By Intermediate

Target

Human immunodeficiency virus 1 (CHEMBL378)
Type ORGANISM
Organism Human immunodeficiency virus 1

Publication

Direct inactivation of human immunodeficiency virus type 1 by a novel small-molecule entry inhibitor, DCM205.
Duong YT, Meadows DC, Srivastava IK, Gervay-Hague J, North TW.
Antimicrob Agents Chemother (2007) 51 : 1780 -1786
PubMed 17307982 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 1 5.64 5.64

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL190009 1 5.64

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL190009 EC50 = 2300.0 nM 5.64