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Assay Detail

CHEMBL936308

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Binding
Binding affinity to ADP-ribosylation factor 1 expressed HEK293 cells by surface plasmon resonance analysis
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Cell Type HEK293
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

ADP-ribosylation factor 1 (CHEMBL5985)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Small-molecule synergist of the Wnt/beta-catenin signaling pathway.
Zhang Q, Major MB, Takanashi S, Camp ND, Nishiya N, Peters EC, Ginsberg MH, Jian X, Randazzo PA, Schultz PG, Moon RT, Ding S.
Proc Natl Acad Sci U S A (2007) 104 : 7444 -7448
PubMed 17460038 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Kd 1 6.21 6.21

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL259181 1 6.21

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL259181 Kd = 620.0 nM 6.21