Assay Detail
Binding
CHEMBL936659
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding affinity to CB2 receptor
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
Identification of novel cannabinoid CB1 receptor antagonists by using virtual screening with a pharmacophore model.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 5 | 6.14 | 7.68 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL376700 | — | — | 1 | 7.68 |
| CHEMBL412071 | — | — | 1 | 5.64 |
| CHEMBL412262 | IBIPINABANT | 2.0 | 1 | 5.10 |
| CHEMBL111 | RIMONABANT | 4.0 | 1 | - |
| CHEMBL411481 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL376700 | — | Ki | = | 21.0 | nM | 7.68 |
| CHEMBL412071 | — | Ki | = | 2312.0 | nM | 5.64 |
| CHEMBL412262 | IBIPINABANT | Ki | = | 7943.0 | nM | 5.10 |
| CHEMBL111 | RIMONABANT | Ki | > | 1000.0 | nM | - |
| CHEMBL411481 | — | Ki | > | 10000.0 | nM | - |