Assay Detail
Functional
CHEMBL936737
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Effect on 5-HT2A-mediated penile erection in rat
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Rattus norvegicus |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Synthesis and structure-activity relationships of a series of benzazepine derivatives as 5-HT2C receptor agonists.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 2 | 6.81 | 7.03 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL407909 | — | — | 1 | 7.03 |
| CHEMBL262862 | — | — | 1 | 6.58 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL407909 | — | EC50 | = | 93.0 | nM | 7.03 |
| CHEMBL262862 | — | EC50 | = | 260.0 | nM | 6.58 |