Assay Detail
Binding
CHEMBL937800
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Inhibition of rat intestinal sucrase
6
Total Activities
3
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Rattus norvegicus |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Alpha-glucosidase inhibitor from Kothala-himbutu (Salacia reticulata WIGHT).
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 6.06 | 6.73 |
| Ki | 3 | 6.79 | 7.28 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL460255 | — | — | 2 | 7.28 |
| CHEMBL1208974 | SALACINOL | — | 2 | 6.70 |
| CHEMBL1093264 | KOTALANOL | — | 2 | 6.38 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL460255 | — | Ki | = | 52.0 | nM | 7.28 |
| CHEMBL460255 | — | IC50 | = | 186.0 | nM | 6.73 |
| CHEMBL1208974 | SALACINOL | Ki | = | 200.0 | nM | 6.70 |
| CHEMBL1093264 | KOTALANOL | Ki | = | 420.0 | nM | 6.38 |
| CHEMBL1093264 | KOTALANOL | IC50 | = | 1370.0 | nM | 5.86 |
| CHEMBL1208974 | SALACINOL | IC50 | = | 2510.0 | nM | 5.60 |