Assay Detail
Functional
CHEMBL938323
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Antiviral activity against TK+ Cowpox virus Delta crmA in HFF cells after 48 hrs by beta-galactosidase assay
8
Total Activities
8
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Cowpox virus |
| Cell Type | HFF |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Publication
Selective phosphorylation of antiviral drugs by vaccinia virus thymidine kinase.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 8 | 5.66 | 6.05 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL382702 | — | — | 1 | 6.05 |
| CHEMBL788 | IDOXURIDINE | 4.0 | 1 | 5.96 |
| CHEMBL214082 | — | — | 1 | 5.72 |
| CHEMBL214955 | — | — | 1 | 5.72 |
| CHEMBL443308 | — | — | 1 | 5.72 |
| CHEMBL382253 | — | — | 1 | 5.57 |
| CHEMBL216289 | — | — | 1 | 5.51 |
| CHEMBL5314375 | CIDOFOVIR | 4.0 | 1 | 5.00 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL382702 | — | EC50 | = | 900.0 | nM | 6.05 |
| CHEMBL788 | IDOXURIDINE | EC50 | = | 1100.0 | nM | 5.96 |
| CHEMBL214082 | — | EC50 | = | 1900.0 | nM | 5.72 |
| CHEMBL214955 | — | EC50 | = | 1900.0 | nM | 5.72 |
| CHEMBL443308 | — | EC50 | = | 1900.0 | nM | 5.72 |
| CHEMBL382253 | — | EC50 | = | 2700.0 | nM | 5.57 |
| CHEMBL216289 | — | EC50 | = | 3100.0 | nM | 5.51 |
| CHEMBL5314375 | CIDOFOVIR | EC50 | = | 10000.0 | nM | 5.00 |