Assay Detail
Binding
CHEMBL939337
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Inhibition of wild type EGFR
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 7.32 | 9.92 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL328216 | — | — | 1 | 9.92 |
| CHEMBL387187 | — | — | 1 | 7.68 |
| CHEMBL407534 | — | — | 1 | 6.11 |
| CHEMBL44 | GENISTEIN | 2.0 | 1 | 5.58 |
| CHEMBL35820 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL328216 | — | IC50 | = | 0.12 | nM | 9.92 |
| CHEMBL387187 | — | IC50 | = | 21.0 | nM | 7.68 |
| CHEMBL407534 | — | IC50 | = | 780.0 | nM | 6.11 |
| CHEMBL44 | GENISTEIN | IC50 | = | 2600.0 | nM | 5.58 |
| CHEMBL35820 | — | IC50 | = | 0.006 | nM | - |