Assay Detail
Binding
CHEMBL939367
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Inhibition of HER2
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Target
Receptor tyrosine-protein kinase erbB-2 (CHEMBL1824) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
A systematic interaction map of validated kinase inhibitors with Ser/Thr kinases.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 5.47 | 5.47 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL258940 | FALNIDAMOL | 2.0 | 1 | 5.47 |
| CHEMBL120077 | — | — | 1 | - |
| CHEMBL406375 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL258940 | FALNIDAMOL | IC50 | = | 3400.0 | nM | 5.47 |
| CHEMBL120077 | — | IC50 | > | 10000.0 | nM | - |
| CHEMBL406375 | — | IC50 | >= | 10000.0 | nM | - |