Assay Detail
Binding
CHEMBL940637
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of L-type calcium channel in Sprague-Dawley rat caudal artery smooth muscle cells by whole cell patch clamp method
2
Total Activities
1
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Rattus norvegicus |
| Confidence | 5 — Multiple protein complex / RNA |
| Curated By | Autocuration |
Target
Voltage-gated L-type calcium channel (CHEMBL2095177) ↗| Type | PROTEIN FAMILY |
| Organism | Rattus norvegicus |
Publication
Anthracene based compounds as new L-type Ca2+ channel blockers: design, synthesis, and full biological profile.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Activity | 1 | - | - |
| IC50 | 1 | 4.78 | 4.78 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL475745 | — | — | 2 | 4.78 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL475745 | — | IC50 | = | 16500.0 | nM | 4.78 |
| CHEMBL475745 | — | Activity | - | — | - |