Assay Detail
Binding
CHEMBL940662
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Inhibition of human recombinant MMP9 by fluorogenic substrate assay
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Ranking the selectivity of PubChem screening hits by activity-based protein profiling: MMP13 as a case study.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 5.83 | 6.80 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL448246 | — | — | 1 | 6.80 |
| CHEMBL475540 | — | — | 1 | 4.85 |
| CHEMBL473326 | — | — | 1 | - |
| CHEMBL500351 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL448246 | — | IC50 | = | 160.0 | nM | 6.80 |
| CHEMBL475540 | — | IC50 | = | 14000.0 | nM | 4.85 |
| CHEMBL473326 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL500351 | — | IC50 | > | 100000.0 | nM | - |