Skip to main content
Free research Free research Free assay review with research home and workspace preview
Quick search ChEMBL 36
Assay Detail

CHEMBL941606

Review assay metadata, readout intent, target linkage, and publication context from the same page.

ADMET
Cytotoxicity against HEK293T cells after 16 hrs by alamar blue staining
18
Total Activities
18
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type ADMET
Organism Homo sapiens
Cell Type HEK-293T
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

ADMET (CHEMBL612558)
Type ADMET

Publication

2,N6-disubstituted adenosine analogs with antitrypanosomal and antimalarial activities.
Rodenko B, van der Burg AM, Wanner MJ, Kaiser M, Brun R, Gould M, de Koning HP, Koomen GJ.
Antimicrob Agents Chemother (2007) 51 : 3796 -3802
PubMed 17698622 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 18 5.91 5.91

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL477683 PHENYLARSINE OXIDE 1 5.91
CHEMBL515337 1 -
CHEMBL478498 1 -
CHEMBL477280 1 -
CHEMBL477281 1 -
CHEMBL503217 1 -
CHEMBL507999 1 -
CHEMBL477491 1 -
CHEMBL515026 1 -
CHEMBL478169 1 -
CHEMBL518756 1 -
CHEMBL478911 1 -
CHEMBL477682 1 -
CHEMBL510005 1 -
CHEMBL516902 1 -
CHEMBL479007 1 -
CHEMBL478170 1 -
CHEMBL479222 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL477683 PHENYLARSINE OXIDE IC50 = 1240.0 nM 5.91
CHEMBL515337 IC50 > 500000.0 nM -
CHEMBL478498 IC50 > 500000.0 nM -
CHEMBL477280 IC50 - -
CHEMBL477281 IC50 - -
CHEMBL503217 IC50 - -
CHEMBL507999 IC50 - -
CHEMBL477491 IC50 > 500000.0 nM -
CHEMBL515026 IC50 = 228000.0 nM -
CHEMBL478169 IC50 = 167000.0 nM -
CHEMBL518756 IC50 - -
CHEMBL478911 IC50 - -
CHEMBL477682 IC50 - -
CHEMBL510005 IC50 - -
CHEMBL516902 IC50 > 500000.0 nM -
CHEMBL479007 IC50 > 500000.0 nM -
CHEMBL478170 IC50 > 500000.0 nM -
CHEMBL479222 IC50 - -