Assay Detail
Functional
CHEMBL941744
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiviral activity against HIV1 3B replication in H9 cells
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Human immunodeficiency virus 1 |
| Cell Type | H9 |
| Confidence | 1 — Organism |
| Curated By | Intermediate |
Target
Human immunodeficiency virus 1 (CHEMBL378) ↗| Type | ORGANISM |
| Organism | Human immunodeficiency virus 1 |
Publication
Anti-AIDS agents 66: syntheses and anti-HIV activity of phenolic and aza 3',4'-di-O-(-)-camphanoyl-(+)-cis-khellactone (DCK) derivatives.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 7 | 6.19 | 7.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL431573 | — | — | 1 | 7.70 |
| CHEMBL129 | ZIDOVUDINE | 4.0 | 1 | 7.30 |
| CHEMBL392411 | — | — | 1 | 6.11 |
| CHEMBL392143 | — | — | 1 | 5.92 |
| CHEMBL392194 | — | — | 1 | 5.82 |
| CHEMBL240538 | — | — | 1 | 5.68 |
| CHEMBL391139 | — | — | 1 | 4.82 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL431573 | — | EC50 | = | 20.0 | nM | 7.70 |
| CHEMBL129 | ZIDOVUDINE | EC50 | = | 50.0 | nM | 7.30 |
| CHEMBL392411 | — | EC50 | = | 770.0 | nM | 6.11 |
| CHEMBL392143 | — | EC50 | = | 1200.0 | nM | 5.92 |
| CHEMBL392194 | — | EC50 | = | 1500.0 | nM | 5.82 |
| CHEMBL240538 | — | EC50 | = | 2100.0 | nM | 5.68 |
| CHEMBL391139 | — | EC50 | = | 15000.0 | nM | 4.82 |