Assay Detail
Functional
CHEMBL942044
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Antioxidant activity in Wistar rat brain assessed as inhibition of lipid peroxidation
12
Total Activities
12
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Rattus norvegicus |
| Tissue | Brain |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Synthesis and antioxidant properties of substituted 3-benzylidene-7-alkoxychroman-4-ones.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 12 | 4.85 | 4.96 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL249186 | — | — | 1 | 4.96 |
| CHEMBL248801 | — | — | 1 | 4.96 |
| CHEMBL402922 | — | — | 1 | 4.95 |
| CHEMBL248799 | — | — | 1 | 4.92 |
| CHEMBL247559 | — | — | 1 | 4.92 |
| CHEMBL249002 | SAPPANONE A | — | 1 | 4.84 |
| CHEMBL153 | TROLOX | — | 1 | 4.38 |
| CHEMBL250404 | — | — | 1 | - |
| CHEMBL250414 | — | — | 1 | - |
| CHEMBL398692 | — | — | 1 | - |
| CHEMBL401492 | — | — | 1 | - |
| CHEMBL250405 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL249186 | — | IC50 | = | 10960.0 | nM | 4.96 |
| CHEMBL248801 | — | IC50 | = | 10960.0 | nM | 4.96 |
| CHEMBL402922 | — | IC50 | = | 11360.0 | nM | 4.95 |
| CHEMBL248799 | — | IC50 | = | 11880.0 | nM | 4.92 |
| CHEMBL247559 | — | IC50 | = | 12110.0 | nM | 4.92 |
| CHEMBL249002 | SAPPANONE A | IC50 | = | 14330.0 | nM | 4.84 |
| CHEMBL153 | TROLOX | IC50 | = | 41570.0 | nM | 4.38 |
| CHEMBL250404 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL250414 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL398692 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL401492 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL250405 | — | IC50 | > | 100000.0 | nM | - |