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Assay Detail

CHEMBL944011

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Functional
Antiproliferation activity against human LnCap cells
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type LNCaP
Confidence 1 — Organism
Curated By Autocuration

Target

LNCaP (CHEMBL612518)
Type CELL-LINE
Organism Homo sapiens

Publication

Discovery of benzisoxazoles as potent inhibitors of chaperone heat shock protein 90.
Gopalsamy A, Shi M, Golas J, Vogan E, Jacob J, Johnson M, Lee F, Nilakantan R, Petersen R, Svenson K, Chopra R, Tam MS, Wen Y, Ellingboe J, Arndt K, Boschelli F.
J Med Chem (2008) 51 : 373 -375
PubMed 18197612 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 6.77 6.77

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL404630 1 6.77

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL404630 IC50 = 170.0 nM 6.77