Assay Detail
Functional
CHEMBL944016
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiproliferation activity against human HCT116 cells in presence of geldanamycin
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | HCT-116 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Discovery of benzisoxazoles as potent inhibitors of chaperone heat shock protein 90.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 7.30 | 7.30 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL404630 | — | — | 1 | 7.30 |
| CHEMBL361078 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL404630 | — | IC50 | = | 50.0 | nM | 7.30 |
| CHEMBL361078 | — | IC50 | >= | 20000.0 | nM | - |