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Assay Detail

CHEMBL944697

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antiprotozoal activity against axenic Leishmania mexicana amastigotes by alamar blue fluorescent dye assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Leishmania mexicana
Confidence 1 — Organism
Curated By Autocuration

Target

Leishmania mexicana (CHEMBL612880)
Type ORGANISM
Organism Leishmania mexicana

Publication

2,N6-disubstituted adenosine analogs with antitrypanosomal and antimalarial activities.
Rodenko B, van der Burg AM, Wanner MJ, Kaiser M, Brun R, Gould M, de Koning HP, Koomen GJ.
Antimicrob Agents Chemother (2007) 51 : 3796 -3802
PubMed 17698622 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 4.93 5.04

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL515337 1 5.04
CHEMBL477084 1 4.82

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL515337 IC50 = 9010.0 nM 5.04
CHEMBL477084 IC50 = 15200.0 nM 4.82