Assay Detail
Functional
CHEMBL944922
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of LPS-induced NO production in mouse BV2 cells
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Mus musculus |
| Cell Type | BV-2 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
In vitro anti-inflammatory activity of 3-O-methyl-flavones isolated from Siegesbeckia glabrescens.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 4.96 | 5.42 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL163316 | 3-O-METHYLQUERCETIN | — | 1 | 5.42 |
| CHEMBL253249 | — | — | 1 | 5.38 |
| CHEMBL253946 | 3,4'-O-DIMETHYLQUERCETIN | — | 1 | 4.96 |
| CHEMBL256147 | TILARGININE | 3.0 | 1 | 4.88 |
| CHEMBL252252 | — | — | 1 | 4.60 |
| CHEMBL50 | QUERCETIN | 3.0 | 1 | 4.53 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL163316 | 3-O-METHYLQUERCETIN | IC50 | = | 3800.0 | nM | 5.42 |
| CHEMBL253249 | — | IC50 | = | 4200.0 | nM | 5.38 |
| CHEMBL253946 | 3,4'-O-DIMETHYLQUERCETIN | IC50 | = | 11100.0 | nM | 4.96 |
| CHEMBL256147 | TILARGININE | IC50 | = | 13200.0 | nM | 4.88 |
| CHEMBL252252 | — | IC50 | = | 25100.0 | nM | 4.60 |
| CHEMBL50 | QUERCETIN | IC50 | = | 29600.0 | nM | 4.53 |