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Assay Detail

CHEMBL945426

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Stimulation of cell proliferation in neonatal CD1 mouse calivaria assessed as increase in [3H]thymidine incorporation
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Mus musculus
Confidence 1 — Organism
Curated By Autocuration

Publication

Discovery of a small molecule antagonist of the parathyroid hormone receptor by using an N-terminal parathyroid hormone peptide probe.
Carter PH, Liu RQ, Foster WR, Tamasi JA, Tebben AJ, Favata M, Staal A, Cvijic ME, French MH, Dell V, Apanovitch D, Lei M, Zhao Q, Cunningham M, Decicco CP, Trzaskos JM, Feyen JH.
Proc Natl Acad Sci U S A (2007) 104 : 6846 -6851
PubMed 17428923 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 1 8.22 8.22

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL506126 1 8.22

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL506126 EC50 = 6.0 nM 8.22