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Assay Detail

CHEMBL945904

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antagonist activity against adenosine A2 receptor
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Confidence 8 — Homologous single protein target
Curated By Intermediate

Target

Adenosine receptor A2a (CHEMBL251)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Multi-target-directed ligands to combat neurodegenerative diseases.
Cavalli A, Bolognesi ML, Minarini A, Rosini M, Tumiatti V, Recanatini M, Melchiorre C.
J Med Chem (2008) 51 : 347 -372
PubMed 18181565 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 7.44 7.44

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL26138 1 7.44

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL26138 Ki = 36.0 nM 7.44