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Assay Detail

CHEMBL945910

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of amyloid beta aggregation at 100 uM
4
Total Activities
4
Compounds Tested
2
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Multi-target-directed ligands to combat neurodegenerative diseases.
Cavalli A, Bolognesi ML, Minarini A, Rosini M, Tumiatti V, Recanatini M, Melchiorre C.
J Med Chem (2008) 51 : 347 -372
PubMed 18181565 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Activity 3 - -
IC50 1 5.70 5.70

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL225567 1 5.70
CHEMBL225198 1 -
CHEMBL32329 1 -
CHEMBL590603 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL225567 IC50 = 2000.0 nM 5.70
CHEMBL225198 Activity = 65.0 % -
CHEMBL32329 Activity = 60.0 % -
CHEMBL590603 Activity = 55.0 % -