Assay Detail
Binding
CHEMBL945911
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Inhibition of human AchE-induced amyloid beta aggregation
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Multi-target-directed ligands to combat neurodegenerative diseases.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 5.00 | 5.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL225567 | — | — | 1 | 5.70 |
| CHEMBL225198 | — | — | 1 | 5.05 |
| CHEMBL345124 | PROPIDIUM | — | 1 | 4.90 |
| CHEMBL194823 | LIPOCRINE | — | 1 | 4.35 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL225567 | — | IC50 | = | 2000.0 | nM | 5.70 |
| CHEMBL225198 | — | IC50 | = | 9000.0 | nM | 5.05 |
| CHEMBL345124 | PROPIDIUM | IC50 | = | 12600.0 | nM | 4.90 |
| CHEMBL194823 | LIPOCRINE | IC50 | = | 45000.0 | nM | 4.35 |