Assay Detail
Functional
CHEMBL946041
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of MHC 2 invariant chain iip10 in mouse splenocytes
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Mus musculus |
| Cell Type | Splenocyte |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
The discovery of odanacatib (MK-0822), a selective inhibitor of cathepsin K.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 9.00 | 9.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL481611 | ODANACATIB | 3.0 | 1 | 9.00 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL481611 | ODANACATIB | IC50 | = | 1.0 | nM | 9.00 |