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Assay Detail

CHEMBL946465

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Decrease in Sindbis virus XJ160 accumulation in BHK21 cells at 2.5 uM by ELISA
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Sindbis virus
Cell Type BHK-21
Confidence 1 — Organism
Curated By Autocuration

Target

Sindbis virus (CHEMBL613725)
Type ORGANISM
Organism Sindbis virus

Publication

Seco-pregnane steroids target the subgenomic RNA of alphavirus-like RNA viruses.
Li Y, Wang L, Li S, Chen X, Shen Y, Zhang Z, He H, Xu W, Shu Y, Liang G, Fang R, Hao X.
Proc Natl Acad Sci U S A (2007) 104 : 8083 -8088
PubMed 17470783 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 1 8.82 8.82

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL486477 PANICULATUMOSIDE C 1 8.82

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL486477 PANICULATUMOSIDE C EC50 = 1.5 nM 8.82