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Assay Detail

CHEMBL946479

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Functional
Antiviral activity against Eastern equine encephalitis virus in BHK21 cells assessed as inhibition of virus-induced cytopathogenicity
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Eastern equine encephalitis virus
Cell Type BHK-21
Confidence 1 — Organism
Curated By Autocuration

Target

Eastern equine encephalitis virus (CHEMBL612725)
Type ORGANISM
Organism Eastern equine encephalitis virus

Publication

Seco-pregnane steroids target the subgenomic RNA of alphavirus-like RNA viruses.
Li Y, Wang L, Li S, Chen X, Shen Y, Zhang Z, He H, Xu W, Shu Y, Liang G, Fang R, Hao X.
Proc Natl Acad Sci U S A (2007) 104 : 8083 -8088
PubMed 17470783 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 1 8.70 8.70

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL486477 PANICULATUMOSIDE C 1 8.70

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL486477 PANICULATUMOSIDE C EC50 = 2.0 nM 8.70