Assay Detail
Functional
CHEMBL946515
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Cytotoxicity against drug-sensitive human KB-3-1 cells after 48 hrs by MTS/PMS assay
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | KB 3-1 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Leishmanicidal, antiplasmodial, and cytotoxic activity of novel diterpenoid 1,2-quinones from Perovskia abrotanoides: new source of tanshinones.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 5.15 | 5.80 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL176049 | RHODAMINE123 | — | 1 | 5.80 |
| CHEMBL485279 | — | — | 1 | 5.30 |
| CHEMBL187460 | CRYPTOTANSHINONE | — | 1 | 5.16 |
| CHEMBL485479 | — | — | 1 | 4.33 |
| CHEMBL519694 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL176049 | RHODAMINE123 | IC50 | = | 1600.0 | nM | 5.80 |
| CHEMBL485279 | — | IC50 | = | 5000.0 | nM | 5.30 |
| CHEMBL187460 | CRYPTOTANSHINONE | IC50 | = | 6900.0 | nM | 5.16 |
| CHEMBL485479 | — | IC50 | = | 46600.0 | nM | 4.33 |
| CHEMBL519694 | — | IC50 | - | — | - |