Assay Detail
Functional
CHEMBL946516
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Cytotoxicity against multidrug-resistant human KBV1 cells after 48 hrs by MTS/PMS assay
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | KB-V1 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Leishmanicidal, antiplasmodial, and cytotoxic activity of novel diterpenoid 1,2-quinones from Perovskia abrotanoides: new source of tanshinones.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 4.90 | 5.25 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL485279 | — | — | 1 | 5.25 |
| CHEMBL187460 | CRYPTOTANSHINONE | — | 1 | 5.12 |
| CHEMBL485479 | — | — | 1 | 4.32 |
| CHEMBL176049 | RHODAMINE123 | — | 1 | - |
| CHEMBL519694 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL485279 | — | IC50 | = | 5600.0 | nM | 5.25 |
| CHEMBL187460 | CRYPTOTANSHINONE | IC50 | = | 7500.0 | nM | 5.12 |
| CHEMBL485479 | — | IC50 | = | 47800.0 | nM | 4.32 |
| CHEMBL176049 | RHODAMINE123 | IC50 | > | 500000.0 | nM | - |
| CHEMBL519694 | — | IC50 | - | — | - |