Assay Detail
Functional
CHEMBL947010
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Antiproliferative activity against human MDA435 cells
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | MDA-MB-435 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Histone deacetylase inhibitors: from bench to clinic.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 5.65 | 6.80 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL113033 | — | — | 1 | 6.80 |
| CHEMBL271800 | — | — | 1 | 5.70 |
| CHEMBL324429 | — | — | 1 | 5.24 |
| CHEMBL112446 | — | — | 1 | 4.85 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL113033 | — | IC50 | = | 160.0 | nM | 6.80 |
| CHEMBL271800 | — | IC50 | = | 2000.0 | nM | 5.70 |
| CHEMBL324429 | — | IC50 | = | 5800.0 | nM | 5.24 |
| CHEMBL112446 | — | IC50 | = | 14000.0 | nM | 4.85 |