Assay Detail
Binding
CHEMBL947976
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Inhibition of TIE2 by HTRF assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Autocuration |
Publication
3-amino-benzo[d]isoxazoles as novel multitargeted inhibitors of receptor tyrosine kinases.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 6.39 | 6.60 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL270084 | — | — | 1 | 6.60 |
| CHEMBL430090 | — | — | 1 | 6.57 |
| CHEMBL269884 | — | — | 1 | 6.00 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL270084 | — | IC50 | = | 249.0 | nM | 6.60 |
| CHEMBL430090 | — | IC50 | = | 270.0 | nM | 6.57 |
| CHEMBL269884 | — | IC50 | = | 1000.0 | nM | 6.00 |