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Assay Detail

CHEMBL948074

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Binding
Binding affinity to 5HT2A receptor
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 8 — Homologous single protein target
Curated By Autocuration

Target

5-hydroxytryptamine receptor 2A (CHEMBL224)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Total synthesis and evaluation of [18F]MHMZ.
Herth MM, Debus F, Piel M, Palner M, Knudsen GM, Lüddens H, Rösch F.
Bioorg Med Chem Lett (2008) 18 : 1515 -1519
PubMed 18187324 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 2 9.57 9.89

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL62919 ALTANSERIN 2.0 1 9.89
CHEMBL74355 VOLINANSERIN 3.0 1 9.24

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL62919 ALTANSERIN Ki = 0.13 nM 9.89
CHEMBL74355 VOLINANSERIN Ki = 0.57 nM 9.24