Assay Detail
Functional
CHEMBL949111
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Growth inhibition of human neonatal foreskin fibroblasts cells
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | Fibroblast |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Histone deacetylase inhibitors: from bench to clinic.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 7 | 6.13 | 6.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL99 | TRICHOSTATIN | 1.0 | 1 | 6.70 |
| CHEMBL318384 | — | — | 1 | 6.46 |
| CHEMBL103508 | — | — | 1 | 6.10 |
| CHEMBL101006 | — | — | 1 | 6.10 |
| CHEMBL103379 | — | — | 1 | 6.08 |
| CHEMBL323346 | — | — | 1 | 5.94 |
| CHEMBL103556 | — | — | 1 | 5.55 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL99 | TRICHOSTATIN | IC50 | = | 200.0 | nM | 6.70 |
| CHEMBL318384 | — | IC50 | = | 350.0 | nM | 6.46 |
| CHEMBL103508 | — | IC50 | = | 800.0 | nM | 6.10 |
| CHEMBL101006 | — | IC50 | = | 800.0 | nM | 6.10 |
| CHEMBL103379 | — | IC50 | = | 830.0 | nM | 6.08 |
| CHEMBL323346 | — | IC50 | = | 1140.0 | nM | 5.94 |
| CHEMBL103556 | — | IC50 | = | 2800.0 | nM | 5.55 |