Assay Detail
Functional
CHEMBL950255
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Agonist activity at mouse PPARalpha by transactivation assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Mus musculus |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Peroxisome proliferator-activated receptor alpha (CHEMBL2128) ↗| Type | SINGLE PROTEIN |
| Organism | Mus musculus |
Publication
Discovery of a novel class of 1,3-dioxane-2-carboxylic acid derivatives as subtype-selective peroxisome proliferator-activated receptor alpha (PPARalpha) agonists.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 2 | 6.50 | 7.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL447533 | — | — | 1 | 7.00 |
| CHEMBL401616 | — | — | 1 | 6.00 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL447533 | — | EC50 | = | 100.0 | nM | 7.00 |
| CHEMBL401616 | — | EC50 | = | 1000.0 | nM | 6.00 |