Assay Detail
Functional
CHEMBL950638
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of Hedgehog signaling in human Shh-L2 cells
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | Shh-L2 |
| Confidence | 3 — Cell-line / Tissue |
| Curated By | Autocuration |
Publication
Inhibition of GLI-mediated transcription and tumor cell growth by small-molecule antagonists.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 5.30 | 5.30 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL472994 | — | — | 1 | 5.30 |
| CHEMBL471728 | — | — | 1 | 5.30 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL472994 | — | IC50 | = | 5000.0 | nM | 5.30 |
| CHEMBL471728 | — | IC50 | = | 5000.0 | nM | 5.30 |