Assay Detail
Binding
CHEMBL952690
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Binding affinity to beta2 adrenoceptor
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Intermediate |
Publication
Antagonists of the calcium receptor I. Amino alcohol-based parathyroid hormone secretagogues.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 7 | 7.54 | 9.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL487508 | — | — | 1 | 9.00 |
| CHEMBL486278 | — | — | 1 | 8.89 |
| CHEMBL504479 | — | — | 1 | 7.68 |
| CHEMBL491251 | — | — | 1 | 7.68 |
| CHEMBL523475 | — | — | 1 | 7.64 |
| CHEMBL487507 | — | — | 1 | 6.52 |
| CHEMBL2112075 | — | — | 1 | 5.37 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL487508 | — | IC50 | = | 1.0 | nM | 9.00 |
| CHEMBL486278 | — | IC50 | = | 1.3 | nM | 8.89 |
| CHEMBL504479 | — | IC50 | = | 21.0 | nM | 7.68 |
| CHEMBL491251 | — | IC50 | = | 21.0 | nM | 7.68 |
| CHEMBL523475 | — | IC50 | = | 23.0 | nM | 7.64 |
| CHEMBL487507 | — | IC50 | = | 300.0 | nM | 6.52 |
| CHEMBL2112075 | — | IC50 | = | 4300.0 | nM | 5.37 |