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Assay Detail

CHEMBL954830

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of monoglyceride lipase in rat brain membrane
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Rattus norvegicus
Tissue Brain
Subcellular Membrane
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Monoglyceride lipase (CHEMBL3321)
Type SINGLE PROTEIN
Organism Rattus norvegicus

Publication

Synthesis and quantitative structure-activity relationship of fatty acid amide hydrolase inhibitors: modulation at the N-portion of biphenyl-3-yl alkylcarbamates.
Mor M, Lodola A, Rivara S, Vacondio F, Duranti A, Tontini A, Sanchini S, Piersanti G, Clapper JR, King AR, Tarzia G, Piomelli D.
J Med Chem (2008) 51 : 3487 -3498
PubMed 18507372 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 4.00 4.00

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL483697 1 4.00

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL483697 IC50 = 100000.0 nM 4.00